Biomedicines, Free Full-Text
Por un escritor de hombre misterioso
4.5 (488) En stock
Artemisia annua L. has long been known for its medicinal properties and isolation of ingredients whose derivatives are used for therapeutic purposes. The CYP2B6 and CYP3A4 enzymes belong to a large family of cytochrome P450 enzymes. These enzymes are involved in the metabolism of drugs and other xeonobiotics. It is known that various compounds can induce or inhibit the activity of these enzymes. The aim of this study was to investigate the nature of the inhibitory effect of Artemisia annua extract on CYP2B6 and CYP3A4 enzymes, as well as the type of inhibition, the presence of reversible or pseudo-irreversible inhibition, and the possible heme destruction. The methanolic extract of Artemisia annua showed an inhibitory effect on CYP2B6 (by almost 90%) and CYP3A4 enzymes (by almost 70%). A significant decrease in heme concentration by 46.8% and 38.2% was observed in different assays. These results clearly indicate that the studied plant extracts significantly inhibited the activity of CYP2B6 and CYP3A4 enzymes. Moreover, they showed irreversible inhibition, which is even more important for possible interactions with drugs and dietary supplements.
Biomedicines, Free Full-Text, Tacs
Biomedicines, Free Full-Text, kelly godoy coelho
Stressors: Recognizing What Causes Stress – Forbes Health, stress
Biomedicines, Free Full-Text, Contrast Medium
Biomedicines, Free Full-Text, gordon hayward sofascore
Biomedicines, Free Full-Text, serpente google maps
Biomedicines, Free Full-Text, Tacs
Biomedicines, Free Full-Text
Biomedicines, Free Full-Text
Biomedicines, Free Full-Text, Contrast Medium
Biomedicines, Free Full-Text, serpente google maps
Biomedicines An Open Access Journal from MDPI
Biomedicines, Free Full-Text, bronstein meier ii
Biomedicines, Free Full-Text, retina
Biomedicines, Free Full-Text
Artemisia Annua tincture 100 ml
Artemisia annua plant; source of artemisinin.
Artemisia Annua: Todo lo que debes conocer. - Artemisia Annua
- Living dec marco plata Medidas radio 60x90
- Funda protectora con soporte para Playstation Portal, funda de TPU
- Salomon Speedcross 6 Gore-Tex
- Pesas De Vinilo 4 kg. Set 2 unid.
- Candado con alarma CAN563 - Comprar en Heng Lian
- Caja de cables Caja de gestión de cables para ocultar cables en cables enredados para máximo. Afortunado Sencillez